Trial intelligence / Profile preview

PF-08634404 plus atezolizumab and chemotherapy in extensive-stage small cell lung cancer

jRCT2031250576Phase 3Recruiting

Sponsor
Pfizer
Start
Feb 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised trial of PF-08634404 in small cell lung cancer (SCLC) (2 arms), sponsored by Pfizer. Primary endpoints: Phase 2: Confirmed Objective Response Rate (ORR) per RECIST 1.1 (investigator assessment), Phase 2: Number of participants with treatment-emergent adverse events and 1 more. Started Feb 2026; status: recruiting.

02

Drugs

PF-08634404
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Conditions

small cell lung cancer (SCLC)

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