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Maridebart cafraglutide for obstructive sleep apnea in adults with overweight or obesity on PAP therapy
jRCT2031250681Phase 3Recruiting
- Sponsor
- Amgen
- Start
- Dec 2025
- Modality
- Peptide-Protein Conjugates → Peptide Conjugates → Peptides, Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Modified Peptides → Peptides
01
Overview
Phase 3, randomised, double-blind trial in obstructive sleep apnea hypopnea syndrome (OSAHS) and obesity comparing Maridebart Cafraglutide with Placebo (2 arms). Primary endpoint: Change in Apnea-Hypopnea Index from baseline at week 52. Started Dec 2025; status: recruiting.
02
Drugs
maridebart cafraglutide
03
Conditions
obstructive sleep apnea hypopnea syndrome (OSAHS)obesity
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