Trial intelligence / Profile preview

Phase 1/2 study of S241656 (BDTX-4933) in RAS/MAPK mutation-positive solid tumors

jRCT2031250784Phase 2Recruiting

Sponsor
Servier
Start
Apr 2026
Modality
Small Molecules
01

Overview

Phase 2, open-label trial of bdtx-4933 in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC), pancreatic adenocarcinoma (PDAC) and 2 more (13 arms), sponsored by Servier. Primary endpoints: Incidence of dose-limiting toxicities, Number of adverse events and serious adverse events and 1 more. Started Apr 2026; status: recruiting.

02

Drugs

bdtx-4933
03

Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)pancreatic adenocarcinoma (PDAC)colorectal adenocarcinomabiliary cancer

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