Trial intelligence / Profile preview

Phase 2 Platform Trial of Long-acting Antibodies in Moderately to Severely Active Ulcerative Colitis

jRCT2031260002Phase 2Not yet recruiting

Sponsor
Spyre Therapeutics, Inc.
Start
Apr 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
01

Overview

Phase 2, randomised, double-blind trial of SPY001, SPY002 and SPY003 in autoimmune colitis (10 arms), sponsored by Spyre Therapeutics, Inc. Primary endpoint: Clinical remission at Week 12. Planned start Apr 2026; status: not yet recruiting.

02

Drugs

SPY001SPY002SPY003
03

Conditions

autoimmune colitis

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