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M24-560: Telisotuzumab Adizutecan (ABBV-400) plus bevacizumab vs trifluridine/tipiracil (LONSURF) plus bevacizumab in refractory metastatic colorectal cancer

jRCT2031260052Phase 3Recruiting

Sponsor
AbbVie Inc.
Start
Jun 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 3, randomised, open-label trial of telisotuzumab adizutecan in colorectal cancer (CRC) (2 arms), sponsored by AbbVie Inc. Primary endpoints: Objective Response (OR) by BICR and Overall Survival (OS). Started Jun 2026; status: recruiting.

02

Drugs

telisotuzumab adizutecan
03

Conditions

colorectal cancer (CRC)

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