Trial intelligence / Profile preview

Open-label extension study of pelacarsen in Japanese participants from Lp(a)HORIZON

jRCT2031260071Not yet recruiting

Sponsor
Novartis
Start
May 2026
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Open-label, single-arm trial of pelacarsen in cardiac morbidity and lipoprotein(a) hyperlipoproteinemia (Lp(a)), sponsored by Novartis. Primary endpoint: Number of participants with adverse events. Planned start May 2026; status: not yet recruiting.

02

Drugs

pelacarsen
03

Conditions

cardiac morbiditylipoprotein(a) hyperlipoproteinemia (Lp(a))

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