Trial intelligence / Profile preview

Setidegrasib versus docetaxel in previously treated KRAS G12D-mutated advanced non-small cell lung cancer

jRCT2031260120Phase 3Recruiting

Sponsor
Astellas Pharma
Start
Aug 2026
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Setidegrasib with Docetaxel (2 arms). Primary endpoints: Progression-free survival and Overall survival. Started Aug 2026; status: recruiting.

02

Drugs

setidegrasibdocetaxel
03

Conditions

non-small cell lung cancer (NSCLC)

Beyond the preview

Go deeper on jRCT2031260120.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on jRCT2031260120.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call