Trial intelligence / Profile preview

Phase 1 Study of MK-4884 in Advanced/Metastatic Solid Tumors

jRCT2031260123Phase 1Recruiting

Sponsor
Merck & Co.
Start
Jun 2026
Modality
Small Molecules
01

Overview

Phase 1, open-label, single-arm trial of MK-4884 in colorectal cancer (CRC), clear cell renal cell carcinoma (ccRCC), non-small cell lung cancer (NSCLC) and 4 more, sponsored by Merck & Co. Primary endpoints: Dose-limiting toxicities (DLT) and Adverse events (AEs). Started Jun 2026; status: recruiting.

02

Drugs

MK-4884
03

Conditions

colorectal cancer (CRC)clear cell renal cell carcinoma (ccRCC)non-small cell lung cancer (NSCLC)biliary cancerintrahepatic cholangiocarcinoma (ICC)

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