Trial intelligence / Profile preview

IBIS phase I study of indisulam alone and with irinotecan in refractory pediatric solid tumors

jRCT2031260508Phase 1Not yet recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Oct 2026
Modality
Small Molecules, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules, RNA-Targeting Small Molecules → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of indisulam and irinotecan in Non-hematologic malignancy (3 arms), sponsored by Japan Agency for Medical Research and Development. Primary endpoint: Incidence of dose-limiting toxicity. Planned start Oct 2026; status: not yet recruiting.

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Drugs

indisulamirinotecan
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Conditions

Non-hematologic malignancy

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