Trial intelligence / Profile preview

Phase 2 single-arm study of JNJ-101556143 in metastatic androgen pathway modulation-resistant prostate cancer

jRCT2031260554Phase 2Not yet recruiting

Sponsor
Janssen Pharmaceutical
Start
Dec 2026
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of HLD-0915 in metastatic castration-resistant prostate cancer (mCRPC), sponsored by Janssen Pharmaceutical. Primary endpoint: Overall Response Rate. Planned start Dec 2026; status: not yet recruiting.

02

Drugs

HLD-0915
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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