Trial intelligence / Profile preview

PHYOX3 long-term rollover study of DCR-PHXC in primary hyperoxaluria

jRCT2041200091Active, not recruiting

Sponsor
Dicerna Pharmaceuticals, Inc.
Start
Jan 2021
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Open-label, single-arm trial of nedosiran in Primary hyperoxaluria (PH), sponsored by Dicerna Pharmaceuticals, Inc. Primary endpoint: Annual rate of decline in eGFR in participants with PH1. Started Jan 2021; status: active, not recruiting.

02

Drugs

nedosiran
03

Conditions

Primary hyperoxaluria (PH)

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