Trial intelligence / Profile preview

Phase 1b study of eftozanermin alfa with bortezomib + dexamethasone in relapsed or refractory multiple myeloma (Japan)

jRCT2041200103Phase 1Active, not recruiting

Sponsor
AbbVie Inc.
Start
Dec 2020
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
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Overview

Phase 1, open-label trial of eftozanermin in multiple myeloma (MM) (2 arms), sponsored by AbbVie Inc. Primary endpoints: Recommended Phase 2 Dose (RP2D) of eftozanermin alfa in combination with bortezomib and dexamethasone (Safety Lead-In Arm) and Objective Response Rate (ORR) (Dose Expansion Arm). Started Dec 2020; status: active, not recruiting.

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Drugs

eftozanermin
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Conditions

multiple myeloma (MM)

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