Trial intelligence / Profile preview

Phase 1 study of MK-1084 alone and in combinations for KRAS G12C-mutant advanced solid tumors

jRCT2041220034Phase 1Recruiting

Sponsor
Merck & Co.
Start
Aug 2022
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of calderasib in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC) and colorectal cancer (CRC) (6 arms), sponsored by Merck & Co. Primary endpoints: Dose-limiting toxicities, Adverse events and 1 more. Started Aug 2022; status: recruiting.

02

Drugs

calderasib
03

Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)colorectal cancer (CRC)

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