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FORTUNA: AZD2693 in Non-cirrhotic NASH with Fibrosis and PNPLA3 Risk Allele
jRCT2041220155Phase 2Completed
- Sponsor
- AstraZeneca
- Start
- Mar 2023
- Modality
- Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
Phase 2, randomised, double-blind trial in metabolic dysfunction-associated steatohepatitis (MASH) comparing AZD2693 with Placebo (2 arms). Primary endpoint: NASH resolution without worsening of fibrosis at Week 52. Started Mar 2023; status: completed.
02
Drugs
AZD2693
03
Conditions
metabolic dysfunction-associated steatohepatitis (MASH)
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