Trial intelligence / Profile preview

INTerpath-001: Adjuvant V940 (mRNA-4157) plus pembrolizumab vs placebo plus pembrolizumab in high-risk melanoma

jRCT2041230169Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Jun 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
01

Overview

Phase 3, randomised, double-blind trial in melanoma comparing V940 (mRNA-4157) + pembrolizumab with Placebo + pembrolizumab (2 arms). Primary endpoint: Recurrence-Free Survival (RFS). Started Jun 2024; status: active, not recruiting.

02

Drugs

intismeran autogenepembrolizumab
03

Conditions

melanoma

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