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Baxdrostat + dapagliflozin vs placebo + dapagliflozin in chronic kidney disease with hypertension (BaxDuo-Pacific, Japan)

jRCT2041240181Phase 3Recruiting

Sponsor
AstraZeneca
Start
Mar 2025
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial of baxdrostat in chronic kidney disease (CKD), hypertension (HTN) and cardiac morbidity (3 arms), sponsored by AstraZeneca. Primary endpoints: Composite of sustained ≥50% decline in eGFR, Composite endpoint of kidney failure and 1 more. Started Mar 2025; status: recruiting.

02

Drugs

baxdrostat
03

Conditions

chronic kidney disease (CKD)hypertension (HTN)cardiac morbidity

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