Trial intelligence / Profile preview

HERTHENA-Breast-01: Patritumab deruxtecan combinations in HER2-positive advanced breast cancer

jRCT2041250022Phase 2Recruiting

Sponsor
Merck & Co.
Start
Jul 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 2, open-label trial of patritumab deruxtecan in breast cancer (3 arms), sponsored by Merck & Co. Primary endpoints: Safety and tolerability and Antitumor activity. Started Jul 2025; status: recruiting.

02

Drugs

patritumab deruxtecan
03

Conditions

breast cancer

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