Trial intelligence / Profile preview

GLORA-4: Lisaftoclax (APG-2575) + Azacitidine vs Azacitidine in Newly Diagnosed Higher-Risk MDS

jRCT2041260051Phase 3Recruiting

Sponsor
Ascentage Pharma
Start
Jun 2026
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in myelodysplastic syndrome (MDS) comparing Lisaftoclax + Azacitidine with Azacitidine + Placebo (2 arms). Primary endpoint: Overall survival. Started Jun 2026; status: recruiting.

02

Drugs

lisaftoclax
03

Conditions

myelodysplastic syndrome (MDS)

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