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HER2CLIMB-02: Tucatinib plus T-DM1 vs placebo plus T-DM1 in unresectable locally advanced or metastatic HER2-positive breast cancer

jRCT2051200068Phase 3Active, not recruiting

Sponsor
Pfizer
Start
Oct 2020
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial of tucatinib in breast cancer (3 arms), sponsored by Pfizer. Primary endpoints: Safety and tolerability in Japan-specific safety run-in and Progression-free survival (PFS) by investigator per RECIST v1.1. Started Oct 2020; status: active, not recruiting.

02

Drugs

tucatinib
03

Conditions

breast cancer

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