Trial intelligence / Profile preview

REBORN: Cisplatin + irinotecan plus durvalumab for untreated extensive-stage small cell lung cancer

jRCT2051200125Phase 2Completed

Start
May 2021
Modality
Small Molecules, PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of durvalumab, cisplatin and irinotecan in small cell lung cancer (SCLC). Primary endpoint: Proportion of 12-month progression-free survival (central imaging review). Started May 2021; status: completed.

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Drugs

durvalumabcisplatinirinotecan
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Conditions

small cell lung cancer (SCLC)

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