Trial intelligence / Profile preview

LEAP-015

jRCT2051200127Phase 3Completed

Sponsor
Merck & Co.
Start
Feb 2021
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
01

Overview

Phase 3, randomised, open-label trial of lenvatinib, pembrolizumab, oxaliplatin, capecitabine, folinic acid and 1 more in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by Merck & Co. Primary endpoints: Number of participants with dose-limiting toxicities, Number of participants with adverse events and 5 more. Started Feb 2021; status: completed.

02

Drugs

lenvatinibpembrolizumaboxaliplatincapecitabinefolinic acid
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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