Trial intelligence / Profile preview

KEYNOTE-B96 / ENGOT-ov65 pembrolizumab plus paclitaxel ± bevacizumab in platinum-resistant ovarian cancer

jRCT2051210184Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Apr 2022
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
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Overview

Phase 3, randomised, double-blind trial in epithelial ovarian cancer (EOC), fallopian tube cancer (PFTC), primary peritoneal cancer (PPC) and 1 more comparing Pembrolizumab arm with Placebo arm (2 arms). Primary endpoint: Progression-free survival (PFS) by investigator per RECIST 1.1. Started Apr 2022; status: active, not recruiting.

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Drugs

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Conditions

epithelial ovarian cancer (EOC)fallopian tube cancer (PFTC)primary peritoneal cancer (PPC)ovarian cancer

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