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OP-07 study for delayed methotrexate elimination during methotrexate-leucovorin rescue

jRCT2051220026Completed

Sponsor
Ohara Pharmaceutical Co., Ltd.
Start
Jul 2022
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Countries
1
01

Overview

Open-label, single-arm trial of glucarpidase in Methotrexate overdose, sponsored by Ohara Pharmaceutical Co., Ltd. Primary endpoints: Adverse events and Blood methotrexate concentration 48 hours after the initial dose of OP-07. Started Jul 2022; status: completed.

02

Drugs

glucarpidase
03

Conditions

Methotrexate overdose

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