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Phase 2 platform study of novel immunotherapy combinations in previously untreated PD-L1-high advanced or metastatic non-small-cell lung cancer

jRCT2051220100Phase 2Active, not recruiting

Sponsor
GSK
Start
Oct 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 2, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Dostarlimab + belrestotug, Dostarlimab + GSK6097608 and Pembrolizumab (3 arms). Primary endpoint: Objective response rate. Started Oct 2020; status: active, not recruiting.

02

Drugs

dostarlimabbelrestotugnelistotugpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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