Trial intelligence / Profile preview

STAR-221 in untreated advanced gastric, gastroesophageal junction, and esophageal adenocarcinoma

jRCT2051220179Phase 3Active, not recruiting

Sponsor
Taiho Pharmaceutical Co., Ltd.
Start
Jun 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, open-label trial in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma and esophageal adenocarcinoma (EAC) comparing Domvanalimab + zimberelimab + chemotherapy with Nivolumab + chemotherapy (2 arms). Primary endpoint: Overall survival. Started Jun 2023; status: active, not recruiting.

02

Drugs

domvanalimabzimberelimabnivolumab
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)

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