Trial intelligence / Profile preview

Switch to doravirine/islatravir vs continued bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed HIV-1

jRCT2051230003Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Apr 2023
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial of doravirine + islatravir in Human immunodeficiency virus infection type 1 (2 arms), sponsored by Merck & Co. Primary endpoints: Percentage of participants with HIV-1 RNA ≥50 copies/mL at Week 48, Percentage of participants who experience adverse events through Week 48 and 1 more. Started Apr 2023; status: active, not recruiting.

02

Drugs

doravirine + islatravir
03

Conditions

Human immunodeficiency virus infection type 1

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