Trial intelligence / Profile preview

LY3954068 intrathecal single and multiple ascending dose study in early symptomatic Alzheimer's disease

jRCT2051240006Phase 1Recruiting

Sponsor
Eli Lilly and Company
Start
Aug 2024
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Small Molecules
01

Overview

Phase 1, randomised, double-blind trial of LY3954068 in Alzheimer's disease (AD) (4 arms), sponsored by Eli Lilly and Company. Primary endpoints: Part A safety and tolerability and Part B safety and tolerability. Started Aug 2024; status: recruiting.

02

Drugs

LY3954068
03

Conditions

Alzheimer's disease (AD)

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