Trial intelligence / Profile preview

Phase 3 randomized open-label study of Trodelvy versus physician's choice chemotherapy in previously treated endometrial cancer

jRCT2051240165Phase 3Active, not recruiting

Sponsor
Gilead Sciences
Start
Nov 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of sacituzumab govitecan, doxorubicin and paclitaxel in endometrial cancer (EC) and endometrial carcinosarcoma (2 arms), sponsored by Gilead Sciences. Primary endpoints: Progression-Free Survival (PFS) as assessed by Blinded Independent Central Review and Overall Survival (OS). Started Nov 2024; status: active, not recruiting.

02

Drugs

sacituzumab govitecandoxorubicinpaclitaxel
03

Conditions

endometrial cancer (EC)endometrial carcinosarcoma

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