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First-in-human study of IDRX-42 in metastatic or unresectable gastrointestinal stromal tumors

jRCT2051240255Phase 1Active, not recruiting

Sponsor
IDRx
Start
Mar 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
01

Overview

Phase 1, open-label, single-arm trial of IDRX-42 in gastrointestinal stromal tumor (GIST), sponsored by IDRx. Primary endpoints: Treatment-emergent adverse events and laboratory safety and Objective response rate. Started Mar 2025; status: active, not recruiting.

02

Drugs

IDRX-42
03

Conditions

gastrointestinal stromal tumor (GIST)

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