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cAMeLot-2: Bleximenib + Venetoclax + Azacitidine in Newly Diagnosed AML with KMT2A Rearrangements or NPM1 Mutations Ineligible for Intensive Chemotherapy

jRCT2051250029Phase 3Recruiting

Sponsor
Janssen Pharmaceutical
Start
Sep 2025
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial of bleximenib in acute myeloid leukemia (AML) (2 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Complete remission rate and Overall survival. Started Sep 2025; status: recruiting.

02

Drugs

bleximenib
03

Conditions

acute myeloid leukemia (AML)

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