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Phase III randomized trial of BNT327 (Pumitamig) + chemotherapy vs atezolizumab + chemotherapy in first-line extensive-stage small-cell lung cancer

jRCT2051250041Phase 3Recruiting

Sponsor
BioNTech SE
Start
Feb 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial of pumitamig in small cell lung cancer (SCLC) (5 arms), sponsored by BioNTech SE. Primary endpoint: Overall survival. Started Feb 2026; status: recruiting.

02

Drugs

pumitamig
03

Conditions

small cell lung cancer (SCLC)

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