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ROXI-APEX: REGN7508 vs apixaban vs enoxaparin for VTE prophylaxis after total knee arthroplasty

jRCT2051250082Phase 3Recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Oct 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, open-label trial of REGN7508 in venous thromboembolism (VTE) (3 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoint: Incidence of composite asymptomatic or symptomatic venous thromboembolism (including VTE-related death). Started Oct 2025; status: recruiting.

02

Drugs

REGN7508
03

Conditions

venous thromboembolism (VTE)

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