Trial intelligence / Profile preview

B440-2 triple combination therapy in unresectable malignant pleural mesothelioma

jRCT2051250111Phase 1Recruiting

Start
Apr 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Live Biotherapeutic Products → Microbiome Therapeutics, Vaccines & Immunotherapeutics
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of nivolumab, ipilimumab and B440 in pleural mesothelioma. Primary endpoints: Safety evaluation and Objective response rate. Started Apr 2026; status: recruiting.

02

Drugs

nivolumabipilimumabB440
03

Conditions

pleural mesothelioma

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