Trial intelligence / Profile preview

GVV858 with or without endocrine therapy in HR+/HER2- breast cancer and other advanced solid tumors

jRCT2051250232Phase 2Recruiting

Sponsor
Novartis
Start
Feb 2026
Modality
Small Molecules
01

Overview

Phase 2, open-label trial of GVV858 in breast cancer, Nonhematologic neoplasms and castration-resistant prostate cancer (CRPC) (5 arms), sponsored by Novartis. Primary endpoints: Incidence and severity of dose-limiting toxicities (DLTs), Incidence and severity of adverse events (AEs) and serious adverse events (SAEs) and 2 more. Started Feb 2026; status: recruiting.

02

Drugs

GVV858
03

Conditions

breast cancerNonhematologic neoplasmscastration-resistant prostate cancer (CRPC)

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