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Phase III comparison of NXT007 versus emicizumab prophylaxis in hemophilia A

jRCT2051250252Phase 3Recruiting

Sponsor
Chugai Pharmaceutical Co., Ltd.
Start
Jun 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, open-label trial in hemophilia A comparing NXT007 prophylaxis with Emicizumab prophylaxis (2 arms). Primary endpoint: Annualized number of treated bleeds (ABR). Started Jun 2026; status: recruiting.

02

Drugs

zemocimigemicizumab
03

Conditions

hemophilia A

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