Trial intelligence / Profile preview

TREVI-OC-02 maintenance study of torvutatug samrotecan plus bevacizumab versus bevacizumab alone in HRD-negative advanced ovarian cancer

jRCT2051260207Recruiting

Sponsor
AstraZeneca
Start
Oct 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
01

Overview

Randomised trial in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) comparing Torvutatug samrotecan + Bevacizumab with Bevacizumab (2 arms). Primary endpoint: Progression-free survival. Started Oct 2026; status: recruiting.

02

Drugs

torvutatug samrotecanbevacizumab
03

Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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