Trial intelligence / Profile preview

ATHENA: AZD5851 GPC3-directed CAR-T in advanced hepatocellular carcinoma

jRCT2053250014Phase 2Not yet recruiting

Sponsor
AstraZeneca
Start
May 2025
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Vaccines & Immunotherapeutics, Gene Therapies
01

Overview

Phase 2, open-label, single-arm trial of AZD5851 in hepatocellular carcinoma (HCC), sponsored by AstraZeneca. Primary endpoint: Safety and tolerability of AZD5851. Planned start May 2025; status: not yet recruiting.

02

Drugs

AZD5851
03

Conditions

hepatocellular carcinoma (HCC)

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