Trial intelligence / Profile preview

LIBRETTO-432 adjuvant selpercatinib in RET fusion-positive NSCLC

jRCT2061210041Phase 3Active, not recruiting

Sponsor
Eli Lilly and Company
Start
Dec 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Selpercatinib with Placebo (2 arms). Primary endpoint: Event-Free Survival. Started Dec 2021; status: active, not recruiting.

02

Drugs

selpercatinib
03

Conditions

non-small cell lung cancer (NSCLC)

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