Trial intelligence / Profile preview

TROPION-Lung07 in first-line advanced non-squamous NSCLC

jRCT2061220066Phase 3Active, not recruiting

Sponsor
Daiichi Sankyo Co., Ltd.
Start
Dec 2022
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of darunavir + cobicistat, pembrolizumab, carboplatin, cisplatin and pemetrexed in non-small cell lung cancer (NSCLC), sponsored by Daiichi Sankyo Co., Ltd. Primary endpoints: Progression-free survival by blinded independent central review in all randomized participants, Progression-free survival by blinded independent central review in TROP2 NMR-positive randomized participants and 2 more. Started Dec 2022; status: active, not recruiting.

02

Drugs

darunavir + cobicistatpembrolizumabcarboplatincisplatinpemetrexed
03

Conditions

non-small cell lung cancer (NSCLC)

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