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Phase 2 PK and Safety Study of Sotatercept Weight-based vs Weight-banded Dosing in PAH

jRCT2061240077Phase 2Completed

Sponsor
Merck & Co.
Start
Jan 2025
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
01

Overview

Phase 2, randomised, single-blind trial of sotatercept in pulmonary arterial hypertension (PAH) (2 arms), sponsored by Merck & Co. Primary endpoints: Steady-state average serum concentration of sotatercept and Adverse events and discontinuations due to adverse events. Started Jan 2025; status: completed.

02

Drugs

sotatercept
03

Conditions

pulmonary arterial hypertension (PAH)

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