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UplighTED phase 3 study of subcutaneous efgartigimod PH20 in adults with thyroid eye disease

jRCT2061240092Phase 3Completed

Sponsor
argenx
Start
Feb 2025
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial in Graves Orbitopathy (GO) comparing Efgartigimod PH20 SC with Placebo PH20 SC (2 arms). Primary endpoint: Percentage of participants who were proptosis responders. Started Feb 2025; status: completed.

02

Drugs

efgartigimod alfa
03

Conditions

Graves Orbitopathy (GO)

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