Trial intelligence / Profile preview

AZD3632 in Advanced Hematologic Malignancies (MOMENTUM)

jRCT2061250075Phase 1Recruiting

Sponsor
AstraZeneca
Start
Jun 2026
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of AZD3632 in acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) (2 arms), sponsored by AstraZeneca. Primary endpoints: Dose-limiting toxicity (DLT) in Module 1, Dose modification, delay, and discontinuations due to adverse events (AEs) and 1 more. Started Jun 2026; status: recruiting.

02

Drugs

AZD3632
03

Conditions

acute lymphoblastic leukemia (ALL)acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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