Trial intelligence / Profile preview

NIMBLE: Pozelimab + Cemdisiran vs Cemdisiran in Generalized Myasthenia Gravis

jRCT2071220059Recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Dec 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Randomised, double-blind trial of pozelimab and cemdisiran in myasthenia gravis (MG) (4 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoint: Change in Myasthenia Gravis-Activities of Daily Living (MG-ADL) total score. Started Dec 2022; status: recruiting.

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Drugs

pozelimabcemdisiran
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Conditions

myasthenia gravis (MG)

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