Trial intelligence / Profile preview

Phase 2 Study of Efgartigimod PH20 SC in Primary Sjogren's Disease-Associated Dryness

jRCT2071250042Phase 2Active, not recruiting

Sponsor
argenx
Start
Aug 2025
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Therapeutic Enzymes → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, double-blind trial in primary Sjögren's syndrome comparing Efgartigimod PH20 SC with Placebo PH20 SC (2 arms). Primary endpoint: Change from baseline in ESSPRI-dryness at week 24. Started Aug 2025; status: active, not recruiting.

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Drugs

efgartigimod alfa + hyaluronidase-qvfc
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Conditions

primary Sjögren's syndrome

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