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VECTRA-01 AZD2265 vs Standard of Care in PSMA-positive mCRPC (Japan Safety Run-in + Phase 3)

jRCT2071260035Phase 3Recruiting

Sponsor
AstraZeneca
Start
Jul 2026
Modality
Small Molecules
01

Overview

Phase 3, randomised trial in metastatic castration-resistant prostate cancer (mCRPC) comparing AZD2265 monotherapy with Standard-of-care therapy (2 arms). Primary endpoints: Safety (Japan Safety Run-in Sub-study), Radiographic Progression-Free Survival (rPFS) and 1 more. Started Jul 2026; status: recruiting.

02

Drugs

palacaparib
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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