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Phase 2 elacestrant monotherapy in Japanese patients with ER-positive/HER2-negative advanced or metastatic breast cancer with ESR1 mutation after CDK4/6 inhibitor therapy

jRCT2071260044Phase 2Recruiting

Sponsor
Stemline Therapeutics
Start
Aug 2026
Modality
Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of elacestrant in breast cancer, sponsored by Stemline Therapeutics. Primary endpoint: IRC-assessed progression-free survival. Started Aug 2026; status: recruiting.

02

Drugs

elacestrant
03

Conditions

breast cancer

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