Trial intelligence / Profile preview

StrateGIST J: Velzatinib in metastatic/unresectable GIST after multiple prior TKIs

jRCT2071260077Phase 2Not yet recruiting

Sponsor
GSK
Start
Aug 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of IDRX-42 in gastrointestinal stromal tumor (GIST), sponsored by GSK. Primary endpoint: Confirmed objective response rate (ORR). Planned start Aug 2026; status: not yet recruiting.

02

Drugs

IDRX-42
03

Conditions

gastrointestinal stromal tumor (GIST)

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