Trial intelligence / Profile preview

4FRONT-2: Single Intravitreal Injection of 4D-150 vs Aflibercept in nAMD

jRCT2073250103Phase 3Recruiting

Sponsor
4D Molecular Therapeutics
Start
Apr 2026
Modality
Gene Therapies, RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Phase 3, randomised, double-blind trial of 4D-150 in exudative macular degeneration (2 arms), sponsored by 4D Molecular Therapeutics. Primary endpoint: Mean change from baseline in BCVA ETDRS letter score at Week 52. Started Apr 2026; status: recruiting.

02

Drugs

4D-150
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Conditions

exudative macular degeneration

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