Trial intelligence / Profile preview

Phase 1b study of osimertinib combinations with savolitinib or selumetinib in EGFR-mutant advanced non-small cell lung cancer after EGFR TKI progression

jRCT2080222610Phase 1Completed

Sponsor
AstraZeneca
Start
Sep 2014
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of osimertinib, savolitinib and selumetinib in non-small cell lung cancer (NSCLC) and Non-hematologic malignancy (7 arms), sponsored by AstraZeneca. Primary endpoints: Safety, Tolerability and 1 more. Started Sep 2014; status: completed.

02

Drugs

osimertinibsavolitinibselumetinib
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Conditions

non-small cell lung cancer (NSCLC)Non-hematologic malignancy

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