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Safety, tolerability, and pharmacokinetics of subcutaneous treprostinil and LY900014 in healthy Japanese subjects

jRCT2080223225Phase 1

Sponsor
Eli Lilly and Company
Start
Jun 2016
Modality
Recombinant Proteins and Enzymes, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 1, randomised, double-blind trial of treprostinil and insulin lispro in diabetes mellitus type 1 (T1D), type 2 diabetes mellitus (T2DM) and pulmonary arterial hypertension (PAH) (4 arms), sponsored by Eli Lilly and Company. Primary endpoints: Safety and tolerability of single subcutaneous treprostinil and LY900014 injections and Pharmacokinetics of LY900014 compared with insulin lispro.

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Drugs

treprostinilinsulin lispro
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Conditions

diabetes mellitus type 1 (T1D)type 2 diabetes mellitus (T2DM)pulmonary arterial hypertension (PAH)

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